Лаборатория регуляции внутриклеточного протеолиза.

Избранные публикации

1. 1.Karpov D.S., Grineva E.N., Leinsoo A.T., Nadolinskaia N.I., Danilenko N.K., Tutyaeva V.V., Spasskaya D.S., Preobrazhenskaya O.V., Lysov Y.P., Karpov V.L. (2017) Functional analysis of Debaryomyces hansenii Rpn4 on a genetic background of Saccharomyces cerevisiae. FEMS Yeast Res, fow098.
2. 2.Kuzmenko Y.V., Starodubova E.S., Shevcova A.S., Latanova A.A., Preobrazhenskaia O.V., Timofeev A.V., Karganova G.G., Karpov V.L. (2017) Protective properties of NS1 are affected by its intracellular degradation and localization. J General Virology, 98, 50-55.
3. 3.Morozov A.V., Kulikova A.A., Astakhova T.M., Mitkevich V.A., Burnysheva K.M., Adzhubei A.A., Erokhov P.A., Evgen'ev M.B., Sharova N.P., Karpov V.L., Makarov A.A. (2016) Amyloid-β Increases Activity of Proteasomes Capped with 19S and 11S Regulators. J Alzheimers Dis, 54 (2), 763-776.
4. 4.Kuzmenko Y.V., Smirnova O.A., Ivanov A.V., Starodubova E.S., Karpov V.L. (2016) Nonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway. Intervirology, 59 (2), 111-117.
5. 5.Bobkova N.V., Evgen'ev M., Garbuz D.G., Kulikov A.M., Morozov A., Samokhin A., Velmeshev D., Medvinskaya, I.Nesterova, A.Pollock, E.Nudler. (2015) Exogenous Hsp70 delays senescence and improves cognitive function in aging mice. Proc Natl Acad Sci USA, 112 (52), 16006-16011.
6. 6.Morozov A.V., Spasskaya D.S., Karpov D.S., Karpov V.L. (2014) The central domain of yeast transcription factor Rpn4 facilitates degradation of reporter protein in human cells». FEBS Lett, 588 (20), 3713-3719.
7. 7.Karpov D.S., Spasskaya D.S., Tutyaeva V.V., Mironov A.S., Karpov V.L. (2013) Proteasome inhibition enhances resistance to DNA damage via upregulation of Rpn4-dependent DNA repair genes. FEBS Lett, 587 (18), 3108-3114.
8. 8.Starodubova E., Boberg A., Ivanov A., Latyshev O., Petrakova N., Kuzmenko Y., Litvina M., Chernousov A., Kochetkov S., Karpov V., Wahren B., Isaguliants M.G. (2010) Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization. Vaccine, 28 (8), 1975-1986.
9. 9.Karpov D.S., Tiutiaeva V.V., Karpov V.L. (2008) Mapping of yeast Rpn4p transactivation domains. FEBS Lett, 582 (23), 3459-3464.
10. 10.Starodubova E.S., Boberg A., Litvina M., Morozov A., Petrakova N.V., Timofeev A., Latyshev O., Tunitskaya V., Wahren B., Isaguliants M.G., Karpov V.L. (2008) HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response. Vaccine, 26 (40), 5170-5176.