Лаборатория молекулярных механизмов иммунитета.

Избранные публикации

1. 1.Gogoleva V.S., Drutskaya M.S., Vorontsov A.I., Atretkhany K.N., Belogurov A.A. Jr, Kruglov A.A., Nedospasov S.A. Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation. (2024) European Journal of Immunology e2350977. doi: 10.1002/eji.202350977.
2. 2.Kruglov A.A., Bondareva M.A., Gogoleva V.S., Semin I.K., Astrakhantseva I.V., Zvartsev R.V., Lunin A.A., Apolokhov V.D., Shustova E.Yu., Volok V.P., Ustyugov A.A., Ishmukhametov A.A., Nedospasov S.A., Kozlovskaya L.I., Drutskaya M.S. Inactivated whole virion vaccine protects K18-hACE2 Tg mice against Omicron SARS-CoV-2 variant via cross-reactive T cells and non-neutralizing antibody responses. (2024) European Journal of Immunology. 54(3):e2350664.
3. 3.Gorshkova E.A., Gubernatorova E.O., Dvorianinova E.M., Yurakova T.R., Marey M.V., Averina O.A., Holtze S., Hildebrandt T.B., Dmitriev A.A., Drutskaya M.S., Vyssokikh M.Y., Nedospasov S.A. (2023) Macrophages from naked mole-rat possess distinct immunometabolic signatures upon polarization. Frontiers in Immunology. 14:1172467.
4. 4.Namakanova O.A., Gorshkova E.A., Zvartsev R.V., Nedospasov S.A., Drutskaya M.S., Gubernatorova E.O. (2022). Therapeutic Potential of Combining IL-6 and TNF Blockade in a Mouse Model of Allergic Asthma. International Journal of Molecular Sciences. 23, 73521.
5. 5.Kruglov A., Drutskaya M., Schlienz D., Gorshkova E., Kurz K., Morawietz L., Nedospasov S. (2020) Contrasting contributions of TNF from distinct cellular sources in arthritis. Annals of Rheumatic Diseases. 2020. 79, 11, 1453 – 1459.
6. 6.Gubernatorova E.O., Gorshkova E.A., Namakanova O.A., Zvartsev R.V., Hidalgo J., Drutskaya M.S., Tumanov A.V., Nedospasov S.A. (2018) Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Frontiers in Immunology, 9, 2718.
7. 7.Atretkhany K.N., Mufazalov I.A., Dunst J., Kuchmiy A., Gogoleva V.S., Andruszewski D., Drutskaya M.S., Faustman D.L., Schwabenland M., Prinz M., Kruglov A.A., Waisman A., Nedospasov S.A. (2018) Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity. Proceedings of the National Academy of Sciences USA, 115, 51, 13051-13056.
8. 8.Efimov G.A., Kruglov A.A., Khlopchatnikova Z.N., Rozov F.N., Mokhonov V .V., Rose-John S. Scheller J., Gordon S, Stacey M., Drutskaya M.S. Tillib S.V., Nedospasov S.A. (2016). Cell type-restricted anti-cytokine therapy: TNF inhibition from one pathogenic source. Proceedings of the National Academy of Sciences USA, 113, 11, 3006-3011.
9. 9.Wang X, Chen H, Tian R, Zhang Y, Drutskaya MS, Wang C, Ge J, Fan Z, Kong D, Wang X, Cai T, Zhou Y, Wang J, Wang J, Wang S, Qin Z, Jia H, Wu Y, Liu J, Nedospasov SA, Tredget EE, Lin M, Liu J, Jiang Y, Wu Y. (2017) Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nature Communications, 8, 14091.
10. 10.Kruglov A.A., Grivenninkov S.I., Kuprash D.V., Winsauer C., Prepens S., Seleznik G.M., Eberl G., Littman D., Heikenwalder M., Tumanov A.V., Nedospasov S.A. (2013). Non-redundant function of soluble LTa3 produced by innate lymphoid cells in intestinal homeostasis. Science, 342, 6163, 1243-1246.