Лаборатория дизайна и синтеза биологически активных соединений

Избранные публикации

1. 1.Konkina M.A., Drenichev M.S., Nasyrova D.I., Porozov Yu.B., Alexeev C.S. (2023) Studies on enzymatic transglycosylation catalyzed by bacterial nucleoside deoxyribosyltransferase II and nucleoside phosphorylase for the synthesis of pyrimidine 2′-deoxyribonucleosides containing modified heterocyclic base. Sust. Chem. Pharmacy, 32:101011.
2. 2.Savina E.A., Shumilina T.G., Tumanyan V.G., Anashkina A.A., Il'icheva I.A. (2023) Core promoter regions of antisense and long Intergenic non-coding RNAs. Int. J. Mol. Sci., 24(9):8199.
3. 3.Varizhuk I.V., Tsvetkov V.B., Toropygin I.Yu., Stomakhin A.A., Kolganova N.A., Surzhikov S.A., Timofeev E.N. (2023) The regioselective conjugation of the 15-nt thrombin aptamer with an optimized tripeptide sequence greatly increases the anticoagulant activity of the aptamer. Pharmaceutics, 15(2):604.
4. 4.Savelieva E.M., Zenchenko A.A., Drenichev M.S., Kozlova A.A., Kurochkin N.N., Arkhipov D.V., Chizhov A.O., Oslovsky V.E., Romanov G.A. (2022) In planta, in vitro and in silico studies of chiral N6-benzyladenine derivatives: discovery of receptor-specific S-enantiomers with cytokinin or anticytokinin activities. Int. J. Mol. Sci., 23(19):11334.
5. 5.Drenichev M.S., Alexeev C.S., Kurochkin N.N., Mikhailov S.N. (2018) Use of nucleoside phosphorylases for the preparation of purine and pyrimidine 2′‐deoxynucleosides. Adv. Synth. Catal., 360(2):305-312.
6. 6.Melikhova A.V., Anashkina A.A., Il'icheva I.A. (2022) Evolutionary invariant of the structure of DNA double helix in RNAP II core promoters. Int. J. Mol. Sci., 23(18):10873.
7. 7.Dyrkheeva N.S., Chernyshova I.A., Ivanov G.A., Porozov Y.B., Zenchenko A.A., Oslovsky V.E., Zakharenko A.L., Nasyrova D.I., Likhatskaya G.N., Mikhailov S.N., Lavrik O.I., Drenichev M.S. (2022) In vitro and in silico studies of human tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibition by stereoisomeric forms of lipophilic nucleosides: The role of carbohydrate stereochemistry in ligand-enzyme interactions. Molecules, 27(8):2433.
8. 8.Alexeev C.S., Kulikova I.V., Gavryushov S., Tararov, V.I., Mikhailov S.N. (2018) Quantitative prediction of yield in transglycosylation reaction catalyzed by nucleoside phosphorylases. Adv. Synth. Catal., 360(16):3090-3096.
9. 9.Smirnov I., Kolganova N., Troisi R., Sica F., Timofeev E. (2017) Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12. Mol. Ther. Nucleic Acids, 23:863-871.
10. 10.Drenichev M.S., Oslovsky V.E., Sun L., Tijsma A., Kurochkin N.N., Tararov V.I., Chizhov A.O., Neyts J., Pannecouque C., Leyssen P., Mikhailov, S.N. (2016) Modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71. Eur. J. Med. Chem., 111:84-94.